Premature Ejaculation Pills: How Do They Work?

premature ejaculation pills

In this article, we’ll discuss how Premature Ejaculation pills work.


Premature ejaculation is a common problem faced by at least one out of five men. It is a sexual problem where a man ejaculates abruptly after beginning foreplay or sexual intercourse, without having any control over his ejaculatory prowess. Although it doesn’t really have anything to do with a man’s medical history or physical health, yet early ejaculation can take a toll on one’s self-esteem causing problems in their sex life. 

Premature ejaculation can be a result of both psychological and biological factors. The psychological factors responsible can be depression, performance-anxiety, chronic stress, or exhaustion. However, sexual inexperience or seldom engagement in sexual intercourse can be some reasons too.

The biological factors that make men likely to suffer from PE can be swelling of the prostate gland, inflammation in the urethra, immoderate hormone levels, an imbalance in the neurotransmitter levels, or just genetically inherited problems. 

Thankfully, early ejaculation isn’t a lifetime problem. There’s an abundance of treatments available to help you combat this problem. The best treatment options for premature ejaculation are pills that help impede the process of ejaculation.

Typically, the medications prescribed to men suffering from premature ejaculation are Selective Serotonin Reuptake Inhibitors (SSRIs) such as Zoloft and Paxil or phosphodiesterase type 5 inhibitor (PDE5 inhibitor) like Sildenafil, Tadalafil, etc. 

Types Of Premature Ejaculation Pills 

Premature ejaculation is one of the most common male sexual problems concerning an estimated 39% of the male population with aging or otherwise at least once in life. Nevertheless, it isn’t something to be too frantic about.

Premature ejaculation is very easily curable with a variety of treatments. The best and most reliable method to cure premature ejaculation is pills. 

Premature Ejaculation medication can be divided into two categories:

1. Over-the-counter Medication

Over-the-counter medication consists of pills that are easily available at drugstores, sex shops, or online marketplaces. These types of medications are often ingested after self-diagnosis and don’t involve any expert prescriptions.

Most of these pills work on improving sexual performance using herbal elements like maca, horny goat weed, etc. Since these medications aren’t backed up by science or involve any professional advice, they aren’t always the safest options. However, the medications work well if the condition isn’t too serious or prolonged.

2. Prescription Medications

These are the medications that are often legal and recommended by doctors, depending on the health and tolerance of the patient. The best of these are Selective Serotonin Reuptake Inhibitors (SSRIs), serotonin inducing antidepressant medications used for the treatment of chronic depression among patients.

Even though they haven’t been approved to cure premature ejaculation by the FDA precisely, it can still be a by-product since depression is another psychological cause of premature ejaculation. SSRIs such as sertraline (Zoloft), paroxetine (Paxil), and fluoxetine (Prozac) work effectively. Another popular prescription medication is PDE5 inhibitors like tadalafil (Cialis) and sildenafil (Viagra). 

How Do Premature Ejaculation Pills Work?

Medications that help inhibit ejaculations can be an efficient way to treat PE. Since a general side effect of most antidepressants can be delayed orgasm. These medications work well with both depression and premature ejaculation. However, both SSRIs and PDE5 inhibitors work in their own ways to avoid and cure premature ejaculation.

1. Selective Serotonin Reuptake Inhibitors

SSRIs are antidepressant drugs that can also be used to treat premature ejaculation. Basically, SSRIs work by boosting the serotonin levels in the body to uplift the mood of the patient. However, SSRIs come with significant sexual side effects such as erectile dysfunction and difficulty in reaching orgasm during sexual intercourse. 

Studies show that sertraline (Zoloft) works best when it comes to PE.  Sertraline significantly increases the time required to achieve an orgasm during sexual intercourse, thus preventing early ejaculation.

Men suffering from premature ejaculation can be given regular doses of sertraline (gradually increasing the dosages) and track progress to see how well it actually works for them. 

Different bodies react to the drug differently, thus while some men may see the result within days or weeks of regular dosages, it can take a month for some.

On the other hand, a small percentage of men who participated in such a study faced the problem of anejaculation (the inability to ejaculate after sexual intercourse) after being given the same amount of dosages of sertraline.

2. Phosphodiesterase Type 5 Inhibitors

PDE5 inhibitors like tadalafil (Cialis) and sildenafil (Viagra) are also an effective treatment for premature ejaculation. PDE5 inhibitors help cure erectile dysfunction by improving the blood circulation in the penile area by facilitating a firm erection. Although PDE5 inhibitors don’t actually work directly on premature ejaculation. Studies show that men who used Viagra and Cialis had shown improved ejaculatory control and performance. By increasing the time between attaining an erection and climax, these medications help control untimely ejaculation, even if it’s a by-product. 

Another interesting fact is that it considerably reduces nerve refractory period, which can help men attain a second erection after premature ejaculation. Using PDE5 inhibitors can also result in a confidence boost among men, hence battling performance anxiety. 

Analgesics are drugs used to get relief from pain or to achieve analgesia (the inability to feel pain). Analgesic drugs such as tramadol (Ultram) mainly target the central nervous system, mainly around the penile area, resulting in a delay in ejaculation. It is important to remember that analgesic drugs cannot be consumed with an SSRI. 

Depending on the condition and tolerance of the patient, doctors may even suggest a combination of SSRIs and PDE5 inhibitors, but one mustn’t consume both the drugs at the same time. To avoid any further complications, make sure that all your dosages are regular and well regulated, increasing them gradually as per need. 

Premature Ejaculation Pills: Conclusion

However, always remember that even if PE is a frustrating condition. You need to be patient with the treatment and avoid rushing things. People often tend to rush into medications and want to fight PE as soon as possible. This approach and mindset are still not the healthiest, it might do more harm than good. Some drugs can lead to major side effects if taken in huge amounts. 

Lastly, there’s an abundance of premature ejaculation pills out there. So it may get a little confusing to decide what might work best for you. Some factors that you must consider before choosing a certain medication can be safety, efficiency, and the time period in which the pill works. Make sure to talk to your doctor before consuming any sort of medication for the condition.