• Generic Name : MIFEPRISTONE
  • Brand Name : MIFEPRISTONE
  • Availibility : In Stock
  • Expiry Date : 1/08/2021
  • Average Delivery Time : 10 - 12 Working Days
  • Strength : 200 Mg

Buy Mifepristone | Abortion Pills Online: Uses, Benefits, Side Effects & Precautions

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What is Mifepristone?

Mifepristone, in conjunction with Misoprostol, is effective in terminating a pregnancy. The drugs have the FDA’s approval to be used in terminating pregnancies of less than 70 days. Typically, Mifepristone blocks the action of progesterone (a hormone that maintains pregnancy) and widens the cervix. The cervix widens as a result of the fetus detaching from the walls of the ruptured uterine wall. 

By contrast, Misoprostol, which is taken after Mifepristone, causes the womb to contract, thus expelling the already detached fetus. Misoprostol causes severe abdominal cramps and heavy vaginal bleeding that may last for hours or days.

Unlike Mifepristone, Misoprostol is not swallowed; preferably, it is placed under the tongue wholly, and allowed to dissolve slowly. Breaking, chewing, crushing, or swallowing reduces its efficacy. The recommended dosage is four pills, each 200 mcg (total 800 mcg). 

What are the dosages and administrations of Mifepristone?

To terminate a pregnancy, take both Mifepristone 200mg and Misoprostol 800mcg as advised. First, swallow Mifepristone 200mg, and after that, take 4 Misoprostol pills of 200mcg each. Misoprostol is either administered by a doctor or self-administered by a woman. In case the pregnancy is not terminated, the second dose of Misoprostol 400mcg is administered. 

After taking Mifepristone a patient should return for a checkup after a week or two of administration. This is to confirm if the pregnancy was terminated. A thorough clinical examination or USG scan is carried out. If a fetus is still present, surgical termination is advised; because the fetus is at risk of fetal malformation. 

Mifepristone prescription is meant to terminate intrauterine pregnancy. The efficacy of these pills can be realized when the pregnancy is within nine weeks as per the first day of amenorrhea. In this case, doctors work with the first day of amenorrhea in a 28-day cycle, with ovulation occurring at mid-cycle.

The age of the pregnancy is determined from menstrual history and by clinical examination. In uncertain cases, ultra-sonogram (USG) scan is conducted. If test results are negative, it could be a case of ectopic pregnancy. 

Do not use Mifepristone if you have an intrauterine device (IUD); remove the device first. Again, if Mifepristone fails to terminate the pregnancy, surgical intervention is advised. Similarly, in cases of abortion or severe bleeding, the gynecologist must be able to intervene surgically.

For patients using Mifepristone tablets

A doctor prescribes Mifepristone. The entire treatment is carried out in 3 visits:

  • First, prescription of a single mifepristone tablet after confirming the pregnancy.
  • Second, prescription of four Misoprostol pills. It is done on day 2 or 3.
  • Lastly, checkup visits usually after two weeks. This visit may include a medical test, e.g., a sonogram to confirm the abortion. If any tissues are still present in the womb, you might need surgery to remove them. 

Note that Misoprostol causes bleeding and cramps. This may last anywhere between 2 and 4 weeks. If you have little or no vaginal bleeding, it is crucial to consult your doctor. 

What are the contraindications?

Administration of Mifepristone is contraindicated in patients who have:

  • Allergy to Mifepristone and Misoprostol 
  • An ectopic pregnancy
  • Migraine
  • Intrauterine device 
  • Chronic adrenal failure
  • Bleeding disorders
  • Anticoagulant, corticosteroid therapies
  • Inherited porphyria
  • Severe uncontrolled asthma

Other contraindications not mentioned above may occur. In case of any abnormal signs, talk to your doctor. 

Women using Mifepristone should have access to medical facilities.; because medical emergency treatment in case of an incomplete abortion, blood transfusions, or emergency resuscitation may be needed. 

What are the warnings and precautions?

People with malnutrition, renal failure,  and hepatic failure are advised against taking Mifepristone. Again, the Mifepristone administration must be under the supervision of a certified gynecologist.

Women with chronic diseases like heart disease, hypertension, liver dysfunction, respiratory or kidney disease, insulin-dependent diabetes, severe anemia, or heavy smoking, especially in women above35 years, should proceed with caution because no studies indicate safety and efficacy of the drug under these conditions.

Fetal abnormalities, according to animal studies, can occur after using these pills. After using the drug, it is crucial to confirm that the pregnancy was terminated. Besides, the risk outweighing the benefits that exist in pregnant women.

Soon after using Mifepristone, it is vital to start using contraceptives since another pregnancy may occur. 

Some women may experience a decrease in hemoglobin concentration, hematocrit, and red blood cell count, especially for those who bleed heavily.

Comments on using Misoprostol

Cramps or gastrointestinal symptoms follow the period immediately after using Misoprostol. As such, you need medication to manage these conditions. 

Misoprostol may not be effective in cases where it is administered less than 24 hours or more than 48 hours.

Misoprostol acts between 2 and 24 hours after consumption. Therefore, the patient must be in an ideal place in case she needed emergency medical attention.

While using Misoprostol for abortion, doctors consider the date from the first day of the last menstrual period. This is determined by looking at menstrual history and clinical examination.

If an ectopic pregnancy is suspected or the length of the pregnancy is uncertain, an ultrasonography scan is usually done.     

What are the drug interactions?

No specific studies on drugs or food interaction are conclusive yet. But there is a possibility of ketoconazole, itraconazole, erythromycin, and grapefruit inhibiting the metabolism of Mifepristone. Similarly, dexamethasone, rifampicin, and certain anticonvulsants may induce Mifepristone metabolism.

Misoprostol has no clinical impact on the absorption and antiplatelet effects of aspirin. Studies on Misoprostol had no clinical implications for ibuprofen, diclofenac, piroxicam, aspirin, naproxen, or indomethacin. 

Avoid Antacids containing magnesium during treatment with Mifepristone; it may worsen diarrhea caused by Misoprostol.

In some cases, two drugs are allowed even if interactions occur, while in other cases, there are some restrictions. So, tell your doctor all medications you have been using.

Below is a list of commonly taken drugs. Using Mifepristone with any of these medicines might not be recommended. However, your doctor will decide on the medication procedures and dosages, respectively:

  • Amisulpride
  • Bepridil
  • Cisapride
  • Cyclosporine
  • Dihydroergotamine
  • Dronedarone
  • Ergotamine
  • Fentanyl
  • Fluconazole
  • Ketoconazole
  • Lovastatin
  • Mesoridazine
  • Pimozide
  • Piperaquine
  • Posaconazole
  • Quinidine
  • Saquinavir
  • Simvastatin
  • Sirolimus
  • Sparfloxacin
  • Tacrolimus
  • Terfenadine
  • Thioridazine

Using Mifepristone with the following medicines is usually not recommended, but may be required in some instances. consult your doctor


Alfentanil Degarelix Histrelin Norfloxacin Sertraline
Amiodarone Delamanid Hydrocodone Nortriptyline Sevoflurane
Anagrelide Desipramine Hydroxychloroquine Octreotide Simeprevir
Aripiprazole Deslorelin Hydroxyzine Ofloxacin Siponimod
Aripiprazole Lauroxil Deutetrabenazine Ibutilide Olaparib Sodium Phosphate
Arsenic Trioxide Digoxin Idelalisib Ondansetron Sodium Phosphate, Dibasic
Asenapine Dihydrocodeine Ifosfamide Osimertinib Sodium Phosphate, Monobasic
Astemizole Disopyramide Iloperidone Oxycodone Solifenacin
Azithromycin Dofetilide Imipramine Paliperidone Sorafenib
Benzhydrocodone Dolasetron Indinavir Panobinostat Sotalol
Boceprevir Domperidone Inotuzumab Ozogamicin Pasireotide St John’s Wort
Buprenorphine Donepezil Itraconazole Pazopanib Sufentanil
Buserelin Doxorubicin Ivabradine Pentazocine Sulpiride
Carbamazepine Doxorubicin Hydrochloride Liposome Ivosidenib Phenobarbital Sunitinib
Ceritinib Droperidol Lapatinib Phenytoin Telaprevir
Chloroquine Efavirenz Leuprolide Pimavanserin Telavancin
Chlorpromazine Encorafenib Levofloxacin Pitolisant Telithromycin
Cilostazol Erythromycin Lofexidine Procainamide Tetrabenazine
Ciprofloxacin Escitalopram Lopinavir Prochlorperazine Toremifene
Citalopram Fingolimod Lumefantrine Promethazine Tramadol
Clarithromycin Flecainide Macimorelin Propafenone Trazodone
Clofazimine Fluoxetine Mefloquine Protriptyline Triclabendazole
Clomipramine Foscarnet Meperidine Quetiapine Trifluoperazine
Clozapine Fosphenytoin Methadone Quinine Trimipramine
Cobicistat Gemifloxacin Metronidazole Ranolazine Triptorelin
Codeine Glasdegib Moxifloxacin Ribociclib Vandetanib
Colchicine Gonadorelin Nafarelin Rifabutin Vardenafil
Conivaptan Goserelin Naloxegol Rifampin Vemurafenib
Crizotinib Granisetron Nefazodone Rifapentine Vinflunine
Dabrafenib Halofantrine Nelfinavir Ritonavir Voriconazole
Dasabuvir Haloperidol Nilotinib Salmeterol Ziprasidone
Dasatinib       Zuclopenthixol

What are the side effects?

Mifepristone causes vaginal bleeding and uterine cramping. Cramping causes abdominal pain. 

Other symptoms are nausea, vomiting, and diarrhea. Rarely, some women may experience pelvic pain, headache, and dizziness. In rare cases, women experience pelvic pain, headache, and dizziness.

A woman may experience one or more side effects, and over 90 percent of patients report side effects on the third day. After day 3, the side effects incidence decline progressively. By the 14th day, there might be no effects except for bleeding and spotting.

Mifepristone: Overdose 

According to intolerance studies, no severe side effects have been reported where a single-dose administration of Mifepristone is higher than threefold of dosage for abortion. However, if the drug is ingested in massive amounts, adrenal failure symptoms may be experienced. Under acute intoxication, special treatment, including dexamethasone administration, is advised.

Humans can tolerate a daily dosage of 1600 mcg well with slight symptoms of gastrointestinal discomfort.

Note that the toxic dose of Misoprostol in humans is not determined yet. But typical overdosing signs are tremor, fever, sedation, hypotension, convulsions, abdominal pain breathlessness, diarrhea,  and bradycardia. In cases of overdose, seek medical attention right away.

Where should I store Mifepristone?

Store the drug in a cool, dry place. Ensure that the container is tightly capped, and the drug container is out of reach of pets and children.

Mifepristone: FAQs

Will I vomit after taking Mifepristone pill?

Nausea is a common symptom with Mifepristone. If you feel nauseated or vomit, talk to your doctor as you may need an antiemetic drug

What should I do if accidentally, I swallowed Misoprostol pills?

Swallowing Misoprostol tablets is still safe and effective. However, this is accompanied by some gastrointestinal effects 

Does Mifepristone affect my fertility?

No. Most of the women will resume ovulation within a few weeks. Menstruation, typically, resumes after four weeks. So a woman can become pregnant after a few weeks.

After how long can I resume sexual intercourse?

Avoid Sex for at least a week from the day of treatment.

Are there any psychological implications after the treatment?

It’s highly unlikely. There are no reported cases of any form of depression and anxiety. the risk of mental health problems is less with Mifepristone treatment.


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