Generic RU486

  • Generic Name : Generic RU486
  • Brand Name : Mifepristone
  • Availibility : In Stock
  • Expiry Date : 1/08/2021
  • Average Delivery Time : 10 - 12 Working Days
  • Strength :

Buy Generic RU486 | Mifepristone: Uses, Benefits, Side Effects & Precautions

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What is Generic RU486?

Generic RU486 is used for pregnancy termination when the pregnancy is less than 70 days old. The brand name of this drug is Mifeprex, and the generic name is Mifepristone. The drug is to be used in combination with Misoprostol (Cytotec) for pregnancy termination. Remember, Generic RU486 is approved by the FDA, so it is safe to use.

Generic RU486 pills are light yellow in color and have some inactive ingredients, e.g., microcrystalline cellulose, magnesium stearate, corn starch and colloidal silica anhydrous. The pill works by antagonizing the effect of the hormone progesterone. , the drug cuts the supply of nutrients and oxygen to the fetus by detaching it from the uterine wall. Besides, it causes the widening of the cervix to facilitate the expulsion of the fetus.

Generic RU486 should be swallowed, while Misoprostol is placed under the tongue and left to melt away slowly. Misoprostol (800 mcg) should be taken 2 or 3 days after taking Generic RU486. Misoprostol works by causing the uterine walls to contract, thus pushing out the fetus. The woman experiences heavy bleeding and uterine cramps. In worse cases, it may go for days, but it should last hours.

Generic RU486: Dosages and administrations

The standard dosage for pregnancy termination is one pill with a 200mg concentration, which should be taken with a glass of water, and on an empty stomach, and four tablets of Misoprostol each one 200mcg. The Misoprostol pills are placed under the tongue where they’ll melt away. Again, the Misoprostol is administered on the 2nd or 3rd day after taking Generic RU486.

The administration of Misoprostol should expel the fetus from the uterus within a few hours. If it doesn't happen, then another oral of 400mcg Misoprostol should be administered. These drugs should be administered by a qualified medical practitioner, though it can be self-administered at times.

A follow-up visit is advised to patients using Generic RU486. This should be any day after the 7th and before the 14th day after treatment. The aim is to confirm the complete expulsion of the fetus. If the fetus is still present, then there is a risk for fetal malformation; thus, surgical termination is the viable option.

A gynecologist must assess the gestational age before administering Generic RU486. The age is determined from menstrual history as well as clinical examination. Ultra-sonogram (USG) scan is essential, especially in cases where the age of pregnancy is unclear. At times, gestational assessment results can be negative. Ectopic pregnancy diagnosis can be carried out. Such a pregnancy can be eradicated by an ultra-sonogram (USG) scan.

Pills must only be administered if the pregnancy is not beyond 9 weeks. As per this treatment, doctors use the first day of amenorrhea in a regular 28-day cycle, where ovulation is on the 14th day.

Pregnancy termination using Generic RU486 is carried out in three steps

  1. The first visit is the prescription of a Generic RU486 tablet
  2. Second visit (2 days later) the prescription of 4 Misoprostol pills.
  3. Third visit (2 weeks later) confirmation of the pregnancy status through medical tests such as a sonogram.

Surgery is recommended if the pregnancy was not terminated. Similarly, it can be recommended if some tissues are still present in the uterus.

Do not take these treatments with an intrauterine device in place.

Contraindications for Generic RU486

Some contraindications have been studied and documented. Below is a list, though, not a complete one. If you experience any other symptoms, do not hesitate to tell your doctor.

  • Ectopic pregnancy
  • Migraine issues
  • IUD in place
  • Chronic adrenal failure
  • Bleeding disorders
  • Anticoagulant or/and corticosteroid therapies
  • Inherited porphyria
  • Severe uncontrolled asthma

During the abortion, a patient may need a blood transfusion or emergency resuscitation. Therefore, the patient must have access to adequate medical facilities. This is also applicable in cases of incomplete abortion.

Generic RU486: Warnings & Precautions

Patients with any form of malnutrition, renal failure, and hepatic failure must not use Generic RU486. Still, there isn’t enough data to support the effectiveness and the safety of this drug in women suffering from some chronic conditions notably, cardiac diseases, high blood pressure, heavy smoking, severe anemia, insulin-dependent diabetes, liver dysfunction, and respiratory or kidney disease. Besides, smokers above 35 years should be treated with caution.

The fetus might be malformed if the pregnancy is not eliminated after using Generic RU486. Thus patients must understand the reasons for doctor's visits to confirm complete pregnancy termination.

Heavy vaginal bleeding might lead to conditions such as reduced red blood cell count, hemoglobin concentration, and hematocrit.

Gastrointestinal problems and cramps are common after using Misoprostol. You must buy drugs to alleviate such symptoms.
The effectiveness of the drugs is usually reduced in the case where Misoprostol is taken less than 24 hours and more than 48 hours.

Within 2 to 24 hours of consumption of Misoprostol, pregnancy should occur. A patient must, therefore, bee at an appropriate place.

Drug Interactions

Though no studies on specific drugs and food have carried out, it is highly possible that ketoconazole, itraconazole, erythromycin, and grapefruit could inhibit Generic RU486 metabolism. By contrast, dexamethasone, rifampicin, and certain anticonvulsants may induce the metabolism of Generic RU486.

Misoprostol lacks a significant impact on the absorption and antiplatelet effects of aspirin. Interaction with other NSAIDs like ibuprofen, diclofenac, piroxicam, aspirin, naproxen, or indomethacin showed no clinical impacts.

Notably, antacids with magnesium must be avoided, as they may worsen diarrhea caused by Misoprostol

Doctors restrict the intake of certain drugs together while accepting others even though they might cause some interactions. Thus you must consult your doctor first before using Generic RU486. The following medicines might interact with Generic RU486.

Generic RU486 Drug Interactions

Amisulpride Bepridil Cisapride Cyclosporine Dihydroergotamine Dronedarone
Ergotamine Fentanyl Fluconazole Ketoconazole Lovastatin Mesoridazine
Pimozide Piperaquine Posaconazole Quinidine Saquinavir Simvastatin
Sirolimus Sparfloxacin Tacrolimus Terfenadine Thioridazine  

While the above-mentioned medications might interact with Generic RU486, the ones mentioned below definitely do. Hence, the doctors don't recommend mixing it with the following:

Side Effects of Generic RU486

Alfentanil Amiodarone Anagrelide Aripiprazole Aripiprazole Lauroxil
Arsenic Trioxide Asenapine Astemizole Azithromycin Benzhydrocodone
Boceprevir Buprenorphine Buserelin Carbamazepine Ceritinib
Chloroquine Chlorpromazine Cilostazol Ciprofloxacin Citalopram
Clarithromycin Clofazimine Clomipramine Clozapine Cobicistat
Codeine Colchicine Conivaptan Crizotinib Dabrafenib
Dasabuvir Dasatinib Degarelix Delamanid Desipramine
Deslorelin Deutetrabenazine Digoxin Dihydrocodeine Disopyramide
Dofetilide Dolasetron Domperidone Donepezil Doxorubicin
Droperidol Efavirenz Encorafenib Erythromycin Escitalopram
Fingolimod Flecainide Fluoxetine Foscarnet Fosphenytoin
Gemifloxacin Glasdegib Gonadorelin Goserelin Granisetron
Halofantrine Haloperidol Histrelin Hydrocodone Hydroxychloroquine
Hydroxyzine Ibutilide Idelalisib Ifosfamide Iloperidone
Imipramine Indinavir Inotuzumab Ozogamicin Itraconazole Ivabradine
Ivosidenib Lapatinib Leuprolide Levofloxacin Lofexidine
Lopinavir Lumefantrine Macimorelin Mefloquine Meperidine
Methadone Metronidazole Moxifloxacin Nafarelin Naloxegol
Nefazodone Nelfinavir Nilotinib Norfloxacin Nortriptyline
Octreotide Ofloxacin Olaparib Ondansetron Osimertinib
Oxycodone Paliperidone Panobinostat Pasireotide Pazopanib
Pentazocine Phenobarbital Phenytoin Pimavanserin Pitolisant
Procainamide Prochlorperazine Promethazine Propafenone Protriptyline
Quetiapine Quinine Ranolazine Ribociclib Rifabutin
Rifampin Rifapentine Ritonavir Salmeterol Sertraline
Sevoflurane Simeprevir Siponimod Sodium Phosphate Sufentanil
Solifenacin Sorafenib Sotalol St John’s Wort Sulpiride
Sunitinib Telaprevir Telavancin Telithromycin Tetrabenazine
Toremifene Tramadol Trazodone Triclabendazole Trifluoperazine
Trimipramine Triptorelin Vandetanib Vardenafil Vemurafenib
Ziprasidone Zuclopenthixol Vinflunine Voriconazole Sodium Phosphate, Monobasic
Sodium Phosphate, Dibasic Doxorubicin Hydrochloride Liposome      

Side Effects of Generic RU486

Abdominal pain, diarrhea, headache, dizziness, nausea, and pain are common side effects of Generic RU486.

The drug, rarely causes unusual tiredness and heavy vaginal bleeding.

Less Common Side Effects of Generic RU486

Acidity Belching Anxiety Coughing Fever
Flu-like symptoms Headache Heartburn Indigestion Lightheadedness 
Itchy vagina Reduced strength Painful sex Pale skin Shaking chills
Stomach discomfort Stuffy or runny nose Chest tightness Trouble sleeping Troubled breathing
Chest pain Confusion Cough Fast or weak pulse Feeling unusually cold
Fever Lower back or side pain Muscle pain or stiffness Sweating Unusual or heavy vaginal bleeding
Painful or difficult urination Severe stomach and shoulders pain Unusual bleeding or bruising Pain around the eyes and cheekbones Elevated white or clear vaginal discharge

What Happens if You Overdose on Generic RU486?

Generic RU486 can be taken up to 3 times the recommended dosage for abortion without causing adverse effects. However, massive ingestion leads to the symptoms of adrenal failure. If acute intoxication is suspected in a patient, then treatment, including dexamethasone, should be administered.

Misoprostol toxic dose is not known. The only known problem with an overdose is gastrointestinal problems, even with a dosage of up to 1600 mcg. Notably, overdose signs are tremors, convulsions, sedation, breathlessness, diarrhea, abdominal pain, fever, hypotension, and bradycardia.

Generic RU486: FAQs

Will I vomit after taking the Generic RU486 pill?

Nausea is the common feeling after the consumption of Generic RU486 pill. Doctors may advise taking an antiemetic drug to prevent vomiting.

What to do when you swallow Misoprostol pills?

Swallowing Misoprostol pills has no adverse effects except for few gastrointestinal effects. Otherwise, it is an effective method.

Where should I store Generic RU486?

Always cap the container tightly and place it in a dry and cool place, preferably where pets and children cannot access.

Does Generic RU486 affect my fertility?

Chances are minimal. Clinical evidence state that a normal menstrual cycle is restored in women within four weeks of treatment. This implies that ovulation will occur; thus, a woman can conceive in a few weeks.

When can I resume sexual intercourse after the treatment?

Give yourself at least a week after treatment with Generic RU486.

Will I have any psychological disturbances after treatment?

Mostly no. The risk of mental disturbances such as anxiety and depression are very low with Generic RU486 treatment.

Is it safe to buy online?

Yes. You can safely and discreetly buy Generic RU486 (Mifeprex) online, especially at ReliableMedRx(RMR). The store stocks authentic and affordable drugs besides privacy and speedy delivery.


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