Best Eye Drops for Dry Eyes : Everything That You Need to Know


In this article, we will discuss about the best eye drops for dry eyes in detail.


Dry eyes syndrome or keratoconjunctivitis sicca (KCS) or keratitis sicca, is a fairly common condition. It occurs when there isn’t adequate production of moisture for lubrication of the sclera of the eye.

In addition to this, slight inflammation of the cornea of the eye may occur along with dry eye syndrome. If left untreated or undiagnosed, this condition can lead to pain, ulcer formation, or leave scars on the cornea, along with some loss of vision. However, permanent loss of vision from dry eye is uncommon.

In a homeostatic balance, the eye is moist. This is essential for optical reasons as well as healthy physiology. Various factors, including age, hormonal status, genetics, sex, immune status, innervation status, nutrition, pathogens, and environmental stress, can alter and disrupt this homeostatic equilibrium.

Dry eye can make performing some daily activities very strenuous. These activities include using a computer, reading for an extended period, sewing, or watching a football match on television. Moreover, it can decrease tolerance for dry environments, such as the air inside an airplane or on a particularly warm day.

A very simple way to deal with this problem is to buy the best eye drops for dry eyes. You can get them over the counter for mild cases and with a physician’s prescription for more severe cases.

How To Select Best Eye Drops for Dry Eyes

A variety of eye drops are available for dry eyes. However, different eye drops are specifically suited to people with different pre-existing health conditions.

Eye drops for dry eyes mainly consist of two types. One type contains preservatives to prevent undesired infections or bacterial growth, while the other does not contain any such additives. Contact lens users should always opt for the no-preservative option as excess preservative build-up can destroy the lens.

Eye drops with polyvinyl alcohol, polyvidone, or a cellulose derivative concoction are perfect for the treatment of mild symptoms. Carbomer derivatives are used for moderate cases. Hyaluron derivatives, depending on the percentage of concentration, are for mild, moderate, and severe dry eye cases.

Given below is a list of the best eye drops for dry eyes:

1. Cyclosporine Ophthalmic Drops

This eye drop works by stimulating the lacrimal glands to produce more tears, thereby lubricating the eye. A very common eye drop brand name is Restasis, containing cyclosporine as the active ingredient. Cyclosporine is in a class of medications called immunomodulators.

Restasis works locally in the eye as a partial modulator of the body’s natural immune system. Tear production decreases when lymphocytes, a type of a-granulated white blood cell dies and accumulates in the tear glands.

Restasis reverses this condition, increasing tear production substantially.

Restasis vials containing cyclosporine are to be kept out of the reach of children and pets. Store it away from direct sunlight but it should not come in contact with moisture either.

How to Use:

  • Apply twice a day, 12 hours apart
    These best eye drops for dry eyes are a safe bet for all except those allergic to cyclosporine.

Visit our website to buy Cyclosporine eye drops at an affordable price.

2. Systane Gel Drops

A worthy inclusion in the best eye drops for dry eyes list. They are quite thick and coat the eyes nicely, easing the dry eye discomfort. They also do not tend to make your eyesight blurry as some eye drops do after use.

Once inserted, they make your eyes feel much better for longer because of the nourishing and hydrating gel formula. This gel assortment is one of the best eye drops for dry eyes caused by astigmatism and meibomian gland dysfunction.

More suited for chronic and persistent dry eye syndrome, this medication might require a prescription from your optometrist or ophthalmologist. These Systane Gel Drops are preservative-free and contain aminomethyl propanol, boric acid, edetate disodium, potassium, and sodium chloride.

Store these eye drops at room temperature.

How to Use

  • Use as many times as needed
  • Optimal results obtained when used before going to bed

3. Opcon-A Eye Drops

Opcon-A Eye Drops are the best eye drops for dry eyes for those suffering from allergic reaction bouts. The active ingredients in this eye drop are Naphazoline, a decongestant, and Pheniramine, an antihistamine. Used in instances of allergy-related eye puffiness or redness.

Other ingredients in the Opcon-A Eye Drops include benzalkonium chloride, boric acid, edetate disodium, purified water, sodium borate, and sodium chloride. However, Opcon-A is not preservative-free and can cause your contact lens to lose shape and become discolored. It is also not an eye drop used around the clock. It is only recommended for those having persistent allergic conditions affecting the eyes.

Refer to the storage information printed on the back of the package. Store the dropper bottle upright and at room temperature between 68-77 degrees F (20-25 degrees C), away from moisture and sunlight.

How to Use

  • Apply up to 4 times a day
  • Only use if you have severe eye redness or inflammation

4. Clear Eyes Itchy Eye Drops

A versatile contender in the list of best eye drops for dry eyes, the Clear Eye formula is primarily used to relieve itchiness. The active ingredient in this eye drop is yet again Naphazoline, a decongestant.

Lubricants such as glycerin and polyethylene glycol help protect the eyes from further irritation. Zinc sulfate, an astringent, helps reduce redness and irritation. Blepharitis is a condition that can cause the eyelids to thicken and the eyes to itch and develop crusts. The Clear Eyes Itchy Eye Drops help mitigate this problem.

If a burning sensation is observed in the eyes after application of the eye drops, contact your doctor immediately. This contender in the list of the best eye drops for dry eyes is very safe. However, this is except for the rare chance that someone is allergic to Naphazoline.

How to Use

  • Do not use if the liquid has changed color or is cloudy
  • Instil 1-2 drops in each eye, 4 times daily

5. VISINE Dry Eye Relief Lubricant Eye Drops

Placing 5th in the list for the best eye drops for dry eyes, VISINE Eye Drops are a drugstore budget-friendly option. This eye drop treats very mild cases of keratitis sicca and is safe to use without qualms regularly.

Remove contact lenses before using this product as it is not preservative-free. Do not use if the solution changes color or becomes cloudy. Moreover, do not touch the tip of the container to any surface to avoid contamination and replace the cap instantly after use.

The active ingredients in the original Visine formulation are potassium chloride and tetrahydrozoline hydrochloride.

Tetrahydrozoline hydrochloride is a vasoconstrictor, and therefore constricts the eye’s superficial blood vessels, facilitating lubrication.

These also contain 10 important ingredients found in your natural tears that help moisturize and soothe dry, gritty eyes. Coming in ½ FL OZ (15mL) and 1.0 FL OZ (30 ml) bottles, these eye drops are easy to store. In addition to that, they can also be used up to a month of unsealing.

How to Use

  • Safe to use as many times as needed
  • Only for mild dry eye symptoms and irritation

Here are few easy tips for maintaining good eyesight.

Best Eye Drops for Dry Eyes :Wrapping Up

With such a vast array of the best eye drops for dry eyes available, this ordinary yet recurring problem can be combatted. Our understanding of keratoconjunctivitis sicca (KCS), also known as dry eye syndrome, has changed considerably over recent years. Until lately, the condition was thought to be merely due to aqueous liquid production insufficiency.

Today, it is understood that KCS is a multifactorial disorder caused due to the inflammation of the ocular surface and lacrimal gland, a probable neurotrophic deficiency, and dysfunction of the meibomian gland. This change in the paradigm has led to the development of new and more effective eye drops and medicines.

Treatments that replenish deficient tears include gels and drops in mild to moderate disease. Other treatment procedures such as topical steroids, immunomodulating drugs, antibiotics, autologous serum, and amniotic membrane transplantation may be used in more severe cases. In chronic dry eyes, surgical intervention minimizes tear drainage. Certain conjunctival and lid operations are performed as per the requirements of the afflicted patient.

To sum it all up, it’s seen that keratitis sicca is curable to a major extent in the initial phases. These best eye drops for dry eyes are a utilitarian method of preventing further discomfort in the optic region. For persistent dry eyes, a physician is to be consulted first.